Alteration in NFKBIA and EGFR in Glioblastoma Multiforme
نویسندگان
چکیده
منابع مشابه
Glioblastoma Multiforme in Children, A Case-Report
ABSTRACT: Glioblastoma multiforme is the most malignant primary brain tumor .It usually occurs in the 5th and 6th decades of life and is rare in childern. In this paper a case of glioblastoma multiforme is reported in a ten year - old child who presented with two week's history of headache with no neurological defect.C.T scan revealed å right frontal mass with massive surrounding oedema. He w...
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The aberrant constitutive activation of nuclear factor-κB (NF-κB) has been observed in glioblastomas, while NF-κB inhibitor alpha (NFKBIA) inhibits the NF-κB signaling pathway under several physiological processes. However, the contribution of NFKBIA to glioblastomas is poorly understood. In the present study, using gene sequencing, we identified rs1957106 as a novel single nucleotide polymorph...
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ژورنال
عنوان ژورنال: Neurosurgery
سال: 2011
ISSN: 0148-396X,1524-4040
DOI: 10.1227/01.neu.0000398206.71573.50